Describe the gain-of-function, dominant-negative mutation ofp53. If DNA containing this allele of p53 is transfected intonormal human cells, would we expect those cells to betransformed?

p53: 基因组守护者

神奇的多细胞生物体维持基因TP53家族

p53抑癌基因检测

Targeted Therapy - Abramson Cancer Center | Penn Medicine

Adoptive Cell Therapy | Cancer Research Institute