Describe the gain-of-function, dominant-negative mutation ofp53. If DNA containing this allele of p53 is transfected intonormal human cells, would we expect those cells to betransformed?

p53一个加号是野生型还是突变型

p53: 基因组守护者

What does the primary structure of a protein represent? How are... | Filo

Complex formation of DNA and p53 protein

Protein structure depends on its amino acid sequence and local,... | Filo

Targeted Therapy - Abramson Cancer Center | Penn Medicine

Adoptive Cell Therapy | Cancer Research Institute