SOLVED: Receptor tyrosine kinases (RTKs) can activate multiple signaling pathways. The PI3 kinase' pathway is diagrammed below: You express green fluorescently labeled Akt (GFP-Akt) in cells. Under which of the following conditions would you expect to see fluorescence in the cytoplasm? Choose all that apply Ligand Activated RTKAclivated AktPI3KActivated Bcl2Protein KinasePI 3-kinaseBadBadBclzInactive Bcl2Cell SurvivalBad mutant that cannot be phosphorylated; with ligandWild-type cell; with ligan

mapk信号通路有哪些

Biochemistry_guide on Instagram: "MAPK (Mitogen-Activated Protein Kinase) signaling pathways are crucial for transmitting signals from the cell surface to the DNA in the nucleus. These pathways regulate a variety of cellular activities including growth, proliferation, differentiation, and apoptosis. The three major MAPK pathways are the ERK, JNK, and p38 pathways. 1. **ERK Pathway (Extracellular Signal-Regulated Kinase)** - **Activation**: Typically activated by growth factors and mitogens. - **

The Molecular Interactions of the MAPK Pathway

SOLVED:Two protein kinases, K 1 and K 2, function sequentially in an intracellular signaling pathway. If either kinase contains a mutation that permanently inactivates its function, no response is seen in cells when an extracellular signal is received. A different mutation in K 1 makes it permanently active, so that in cells containing that mutation a response is observed even in the absence of an extracellular signal. You characterize a double-mutant cell that contains K 2 with the inactivating

Dr. Davies on the Potential Utility of ERK Inhibitors in Melanoma