As a neurologist, I am often asked to see patients because they have a magnetic resonance image (MRI) of the brain showing white matter hyperintensities (WMHs). These patients, and the clinicians who refer them to me, want to know the answers to several questions: What are WMHs and what causes them?

White matter changes are visible on magnetic resonance imaging (MRI) as lesions. An MRI report can call white matter changes a few different things, including: Cerebral or subcortical white matter disease or lesions. Microvascular disease. Non-specific white matter changes. T2 hyperintensities (lesions).

2024年5月21日 · Learn what causes spots on an MRI (white matter hyperintensities), including strokes, infections, and multiple sclerosis.

White matter hyperintensities (WMH) of presumed vascular origin, also referred to as leukoaraiosis, are a very common finding on brain magnetic resonance imaging (MRI) or computed tomography (CT) in older subjects and in patients with stroke and dementia.

2009年11月23日 · White matter hyperintensities were associated with an increased risk of stroke (hazard ratio 3.3, 95% confidence interval 2.6 to 4.4), dementia (1.9, 1.3 to 2.8), and death (2.0, 1.6 to 2.7).

2024年3月7日 · Periventricular-white matter hyperintensity (PV-WMH) is featured by gliosis, loosening of the WM, and loss around convoluted venules in perivascular spaces. In contrast, the primary characteristics of deep subcortical-white matter hypersensitivity (DS-WMH) are demyelination, gliosis, and augmented tissue loss as the lesions become serious.

2015年2月17日 · White matter hyperintensities (WMHs) in the brain are the consequence of cerebral small vessel disease, and can easily be detected on MRI.

White matter hyperintensities (WMH) are brain white matter lesions that are hyperintense on fluid attenuated inversion recovery (FLAIR) magnetic resonance imaging (MRI) scans. Larger WMH volumes have been associated with Alzheimer’s Disease (AD) and with cognitive decline.

2023年4月18日 · White matter abnormalities is a general term for lesions affecting the brain and spinal cord. These often involve bright, hyperintense findings on MRI and are responsible for an array of symptoms depending on their location.

2015年6月23日 · White matter hyperintensities (WMH) of presumed vascular origin, also referred to as leukoaraiosis, are a very common finding on brain magnetic resonance imaging (MRI) or computed tomography (CT) in older subjects and in patients with stroke and dementia.