Chemically, it is a 2,3-benzodiazepine. Unlike other anxiolytic benzodiazepines (which are generally 1,4- or 1,5-substituted) however, tofisopam does not have anticonvulsant, sedative, …

2011年1月20日 · Tofisopam (marketed under brand names Emandaxin and Grandaxin) is a 2,3-benzodiazepine drug which is a benzodiazepine derivative. In contrast to classical 1,4 …

2024年1月18日 · Tofisopam is indicated for the short-term management of anxiety and the relief of alcohol withdrawal syndrome. It’s being explored as a potential treatment for …

We now show that tofisopam, 50 mg/kg intraperitoneally (i.p.), administered in parallel to repeated doses of dizocilpine 0.2 mg/kg i.p. can ameliorate dizocilpine-induced prolongation of …

Tofisopam is a benzodiazepine derivative with anxiolytic (anti-anxiety) properties. It belongs to the class of psychoactive drugs and is primarily used for the management of anxiety disorders.

Tofisopam is a benzodiazepine derivative. It is used to treat depression. It functions by regulating the level of a chemical known as catecholamine which is present in the human body. Women …

New clinical reports have recently been published on tofisopam—an anxiolytic drug currently registered as a benzodiazepine—after a long break in this research area. Neurobiological …

Tofisopam is a an unusual benzodiazepine in that it has a 2,3-benzodiazepine ring rather than the classical nitrogen atom positioning at 1,4 [13]. It exists as a set of four isomers, due to the …

Tofisopam (marketed under brand names Emandaxin and Grandaxin) is a 2,3-benzodiazepine drug which is a benzodiazepine derivative. In contrast to classical 1,4-benzodiazepines, the …

This review describes the behavioural and biochemical profile of tofisopam, a 3,4-benzodiazepine that differs considerably in its effects and mechanisms of action from classical 1,4 …