The pyrophosphate bond is also sometimes referred to as a phosphoanhydride bond, a naming convention which emphasizes the loss of water that occurs when two phosphates form a new …

在ATP分子中，核糖和α-磷酸基团由一个酯键连接，α与β，β与γ之间的磷酸基团为焦磷酸键连接。 焦磷酸键 (pyrophosphate bond) 由磷酸缩合而成，是高能键。

Using time-resolved crystallography, we show that hydrolysis of PPi is an intrinsic and critical step of the DNA synthesis reaction catalyzed by dPols. The hydrolysis of PPi occurs after the …

2015年9月15日 · In early years, nucleoside pyrophosphate bond formation was mainly through P(V)–P(V) approaches, including a protected nucleoside benzyl phosphorochloridate …

Pyrophosphate refers to a molecule composed of two inorganic phosphate molecules joined by a hydrolysable ester bond. It is mainly produced as a metabolic by-product in intracellular …

It comprises two inorganic phosphate (or P i) molecules joined by a hydrolysable ester bond (Figure 1). Although pyrophosphate and longer chain polyphosphates can be synthesised …

2015年9月15日 · In this Digest, the chemical synthesis of the pyrophosphate bonds of representative bioactive nucleoside diphosphate analogs, i.e. phosphorus-modified analogs, …

Upon heating crystal 1, it transformed into dehydrated crystal 1′, and further heating to temperatures above 510 K caused the dehydration condensation reactions between adjacent …

This hydrolysis has the effect of pulling the first reaction strongly in the direction of biosynthesis, at the expense of two high-energy phosphate bonds. Studies of human cells have identified two …

Pyrophosphate bond Ligases (syniheiases). Enzymes catalysing the joining together of two molecules coupled with the hydrolysis of a pyrophosphate bond in ADP or a similar …