2023年4月23日 · However, most research has shown that PCT levels display clinical significance in the range of 0.1 to 0.5 ng/mL. Further, research has shown that PCT levels less than 0.1 ng/mL have been shown to have a high negative predictive …

2024年6月9日 · If your blood contains an abnormally high level of procalcitonin, a substance your body produces in response to a bacterial infection, it can indicate that you have sepsis or are likely to develop sepsis.

PCT should only be interpreted within the clinical context to guide treatment strategies. 5. When can PCT be falsely elevated (false positive)? 6. When is PCT falsely decreased (false negative)? 7. PCT misconceptions. 8. What is the PCT cut off for End-Stage Renal Disease? PCT is known to be higher in ESRD due to decreased clearance.

2024年5月10日 · Procalcitonin is a serum biomarker that helps distinguish bacterial infection from other causes of infection or inflammation. In patients with lower respiratory tract infections, procalcitonin can serve as a helpful adjunct to clinical judgment for guiding antibiotic therapy and resolving diagnostic uncertainty.

2021年10月22日 · Interpretation of Procalcitonin Levels As stated above, the reference value for procalcitonin in adults is less than 0.1 ng/mL, and levels greater than 0.25 ng/mL can indicate the presence...

Procalcitonin (PCT), regarded as a biomarker specific for bacterial infections, is used in a variety of clinical settings including primary care, emergency department and intensive care. PCT measurement aids in the diagnosis of sepsis and to guide ...

Slightly high levels of procalcitonin mean that you are unlikely to develop sepsis, but they may be a sign of: A local bacterial infection, such as a urinary tract infection; An infection from another cause, such as a virus; A systemic bacterial infection that is just beginning

Discover how PCT levels can change over the course of an infection with antibiotic use. Learn how to interpret PCT results and understand what they mean.

Levels greater than 0.25 ng/mL may indicate the presence of an infection. If your results show an high level of procalcitonin, it is likely that you have a serious bacterial infection such as sepsis or meningitis. The higher the level, the more serious your infection may be.

Normal Range: Procalcitonin levels between 0 and 0.05 ng/L are considered normal. Low Risk : Levels below 0.5 ng/L suggest a low risk of sepsis. High Risk : Levels above 2 ng/L indicate a moderate to high risk of sepsis, with 10 ng/L or higher indicating severe sepsis.