Poly (amidoamine), or PAMAM, is a class of dendrimer which is made of repetitively branched subunits of amide and amine functionality.

Poly (amidoamine) (PAMAM) dendrimers are hyper-branched polymers with unparalleled molecular uniformity, narrow molecular weight distribution, defined size and shape characteristics and a multi-functional terminal surface. These nanoscale polymers consist of:

PAMAM (polyamidoamine) was introduced in 1985, by Donald A. Tomalia, as a new class of polymers, named ‘starburst polymers’. This important contribution of Professor Tomalia opened a new research field involving nanotechnological approaches.

2001年4月15日 · Poly (amidoamine) (PAMAM) dendrimers are the first complete dendrimer family to be synthesized, characterized and commercialized. Based on this extensive activity, they are recognized as a unique new class of synthetic nanostructures.

2022年12月1日 · PAMAM dendrimers are among the most widely explored family of dendrimers that contains a variable count of carbonyl and primary and tertiary amine groups in their internal branching network along with multifunctional active or passive terminal groups.

2024年7月23日 · PAMAM dendrimers are composed of repetitive branched sub-units of amide and amine functionalities. Their popularity and frequent use in the research literature are thought to stem from their greater biocompatibility compared to other families of dendrimers and their unique physicochemical properties, which were summarised by Jang et al.

Poly (amidoamine) (PAMAM) dendrimers are repetitively branched, three-dimensional molecules, made of amide and amine subunits, possessing unique physiochemical properties.

2014年3月13日 · Poly(amidoamine) (PAMAM) dendrimers are a novel class of spherical, well-designed branching polymers with interior cavities and abundant terminal groups on the surface which can form stable complexes with drugs, plasmid DNA, oligonucleotides, and antibodies.

We present our optimized procedure for post-synthesis (and post-market) purification of a generation 5 PAMAM dendrimer by membrane dialysis and demonstrate its effectiveness and limitations using a representative lot of biomedical grade dendrimer.

2020年7月1日 · Among all of the dendrimers, Poly-amidoamine (PAMAM) dendrimer are used enormously applying materials in supramolecular chemistry. This review described the structure, characteristic, synthesis, toxicity, and surface modification of PAMAM dendrimer.