Emerging evidence indicates the involvement of OT system in several pathophysiological mechanisms influencing brain anatomy, cognition, language, sense of safety and trust and maternal behavior, with the possible use of exogenous administered OT in the treatment of specific neuropsychiatric conditio …

Here we showed that oxytocin modulates expression of circulating proteins involved in inflammation, immunity, and cell signaling pathways, and identified a specific cluster of these proteins impacted by oxytocin that were associated with subsequent reduced caloric intake at the test meal (manuscript under review).

Oxytocin stimulates glucose uptake in skeletal muscle cells through the calcium-CaMKK-AMPK pathway. Deciphering the specific role of G (alphai/o) isoforms: functional selective oxytocin ligands and somatostatin SST5 receptor mutants. Effects of cholesterol manipulation on the signaling of the human oxytocin receptor.

2019年2月8日 · Oxytocin is a neuropeptide involved in animal and human reproductive and social behavior. Three oxytocin signaling genes have been frequently implicated in human social behavior: OXT...

The main signaling pathway is the Gq/PLC/Ins3 pathway, but the MAPK and the RhoA/Rho kinase pathways are also activated, contributing to increased prostaglandin production and direct contractile effect on myometrial cells.

2024年4月17日 · Oxytocin is a neuropeptide associated with both psychological and somatic processes like parturition and social bonding. Although oxytocin homologs have been identified in many species, the...

1999年1月14日 · Oxytocin stimulates glucose uptake in skeletal muscle cells through the calcium-CaMKK-AMPK pathway. Deciphering the specific role of G (alphai/o) isoforms: functional selective oxytocin ligands and somatostatin SST5 receptor mutants. Effects of cholesterol manipulation on the signaling of the human oxytocin receptor.

The main signaling pathway is the Gq/PLC/Ins3 pathway, but the MAPK and the RhoA/Rho kinase pathways are also activated, contributing to increased prostaglandin production and direct contractile effect on myometrial cells.

2020年5月20日 · Conclusion: Emerging evidence indicates the involvement of OT system in several pathophysiological mechanisms influencing brain anatomy, cognition, language, sense of safety and trust and maternal behavior, with the possible use of exogenous administered OT in the treatment of specific neuropsychiatric conditions.

We cataloged 66 molecules belonging to oxytocin signaling pathway, which included 9 protein-protein interactions, 39 post-translational modifications, 14 protein translocation events and 22 activation/inhibition events.