2025年1月1日 · RPE mottling refers to irregular pigmentation changes in the retinal pigment epithelium, which can affect vision. Causes of RPE mottling include aging, genetics, sun exposure, and certain medical conditions such as macular degeneration.

2025年1月1日 · RPE mottling of the macula refers to a specific alteration in the retinal pigment epithelium (RPE) that can be observed during an eye examination. The macula is a small but crucial area of the retina responsible for central vision, allowing you to see fine details and colors.

2021年2月15日 · Combine your clinical observations and knowledge with detailed imaging to put together the full picture of the diagnosis. Interpreting an abnormality on a macular optical coherence tomography (OCT) image can be daunting for practitioners relatively new to OCT.

Macular mottling is evident at an early age with attenuation and narrowing of the retinal arterioles. The pigmentary changes are salt-and-pepper in appearance but there are also areas of RPE atrophy with relative sparing of the fovea.

Pattern dystrophies are a group of autosomal dominant macular diseases characterized by various patterns of pigment deposition within the macula. The primary layer of the retina effected is the retinal pigment epithelium (RPE) which is responsible for removing and recycling waste within the retina.

2010年12月27日 · Examination of the right macula showed nonspecific retinal pigment epithelium (RPE) mottling (figure 1). There was no obvious subretinal fluid present, and the peripheral retinal exam was unremarkable.

2025年1月1日 · RPE mottling and drusen are both related to age-related macular degeneration (AMD), a leading cause of vision loss in older adults. RPE mottling refers to changes in the retinal pigment epithelium, while drusen are small yellow deposits under the retina.

Age-related macular degeneration (AMD) is a condition where the light-sensing cells at the back of the eye (our photoreceptors, called rods and cones) become sick and are slowly destroyed. This results in a loss of vision straight ahead; it degrades our ability to see details.

2019年7月15日 · D rusen, along with pigment mottling, are the earliest clinical signs and a characteristic hallmark of age-related macular degeneration (AMD). 1,2 This is an important clinical finding, as AMD ranks globally as the third leading cause of blindness after cataracts and glaucoma. 2 Since AMD is chronic and progressive, early identification is ...

Pattern dystrophy (PD) of the retinal pigment epithelium (RPE) refers to a heterogeneous group of dominantly inherited macular diseases characterized by the development of a variety of patterns of deposits of the yellow, orange, or gray pigment in the macular area (Figure 1). 1,2 The better-known PDs include butterfly-shaped dystrophy ...