Incidence of infection with staphylococcal and non-staphylococcal bacteria has been shown to decrease with preoperative screening for Methicillin-Resistant Staphylococcus aureus species (MRSA) and Methicillin-Susceptible Staphylococcus Aureus (MSSA) species along with decolonization methods.

The MRSA nasal PCR is most helpful in patients with a highly suspected or definitive pneumonia as colonization in the nares is correlated with presence elsewhere in the respiratory tract. It is less helpful

Rapid detection of Methicillin Resistant Staphylococcus aureus (MRSA) is an important concern for both treatment and implementation of infection control policies. The present study provides an ‘in house’ real-time PCR assay to detect directly nuc, pvl, and mecA genes.

Methicillin Resistant Staphylococcus aureus, PCR - Rapid, direct detection of nasal colonization by MRSA. Aids in the prevention and control of MRSA infections in healthcare settings.

The test utilizes automated PCR for qualitative detection of proprietary sequences for the staphylococcal protein A (spa) gene, the gene for methicillin resistance (mecA), and the staphylococcal MRSA/SA S aureus DNA cassette chromosome mec (SCCmec) inserted into the S aureus chromosomal attB site. The assay includes a sample processing control ...

2023年8月1日 · Real-time PCR to detect MRSA in nasal swab specimens, with results available in approximately two hours, has become the test of choice for many institutions. 2 The data supporting screening with the MRSA nasal PCR to reduce nosocomial transmission is mixed, but it is now well established that MRSA nasal colonization is a risk factor for ...

MRSA/SA is a qualitative RT-PCR test detecting and differentiating between methicillin-resistant Staphylococcus aureus (MRSA), methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant coagulase-negative Staphylococci (MRCoNS).

2019年7月25日 · Purpose: To allow pharmacist ordering of nasal MRSA PCR in order to facilitate de-escalation of empiric antibiotic coverage of MRSA pneumonia. Treatment of pneumonia often lacks microbiological data to streamline empiric antibiotics.

The MRSA PCR assay demonstrated 88.0% sensitivity and 90.1% specificity, with a positive predictive value of 35.4% and a negative predictive value of 99.2%. In patients with pneumonia, the MRSA PCR nasal swab has a poor positive predictive value but an excellent negative predictive value for MRSA pneumonia in populations with low MRSA pneumonia ...

Recent data demonstrate the utility of methicillin-resistant Staphylococcus aureus (MRSA) polymerase chain reaction (PCR) nasal screening to steward anti-MRSA empiric antibiotics in pneumonia. We hypothesize that MRSA PCR nasal swabs would also be effective to rule out other MRSA infection to effectively limit unnecessary antibiotics for any ...