2011年7月8日 · JWH-250 can likely produce this same effect. This tolerance is likely the result of CB1/2 receptor downregulation, similar to the tolerance developed from ∆-9-THC or Cannabis administration as discussed here under the Tolerance heading and in much greater detail in a dedicated thread here: Cannabis and Cannabinoid Tolerance .

2009年10月14日 · Please add your experiences with JWH-250. Please add dosage, route and duration to the top of your post like this: Dosage: 3mg Route: smoked...

2011年10月5日 · As Shampoo already said, those CAS numbers are either fraudulent or CAS numbers of already known JWH-x series compounds (e.g. JWH-250).

2024年11月14日 · Re: Did any one get the FEAR from jwh-081, jwh-200, jwh-250 overdoses? The fact that one needs to "navigate" or be "experienced" to do so, is...

2009年7月19日 · JWH-250 (1-pentyl-3-(2-methoxyphenylacetyl)indole) is an analgesic chemical from the aminoalkylindole family, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors, with a Ki of 11nM at CB1 and 33nM at CB2. Unlike many of the older JWH series compounds, this compound does not have a naphthalene ring, instead occupying this ...

2009年10月14日 · Similarly, JWH-200 and JWH-250 likely have much smaller therapeutic indexes (Ti = LD50/ED50) than the traditional Cannabinoids, ∆-9-THC, CBD and CBN. Treating novel research chemicals as though all of the assumptions regarding safety, efficacy and reliability which we apply to Cannabis somehow hold true with all CBr agonists is reckless and ...

2010年8月11日 · I wonder if there are any reports that users of jwh-081, jwh-200, jwh-250 had experienced the FEAR or some sort of panic or anxiety attacks? Please...

2011年2月23日 · His penguin lives in Missouri and JWH-250 is currently completely legal, but the substance is banned in other states. He was wondering if there are any plans to create a urine test for the substance. From everything he has read he has learned that there is a mouth swab to detect the various JWH compounds, but as far as he knows there is no word ...

2010年7月13日 · I recently acquired a 1.2g bag of jwh-250 from his online supplier and proceeded to get high at least once a day for the past 41 days. Two days ago...

2010年12月19日 · Drugs: Heroin, 5-MeO-DALT, JWH-250 Dose: 8mg, 10mg Route: IV, Vaporization _____ _____ _____ This...