Disturbances of gait occur in all stages of Huntington’s disease (HD) including the premanifest and prodromal stages. Individuals with HD demonstrate the slower speed of gait, shorter stride length, and increased variability of gait parameters as compared to controls; cognitive disturbances in HD often compound these differences.

2014年10月1日 · Huntington’s disease (HD) is an autosomal dominant inherited neurodegenerative disorder that presents with characteristic gait changes, including decreased walking speed, step initiation difficulties - and a variable stepping pattern -.

We investigated 13 patients with Huntington's disease and assessed gait by filming and by gait analyzer before and after increasing haloperidol dosage, until chorea was suppressed or side effects intervened. The severity of chorea and ataxia was scored blindly from videotapes. Gaits were abnormal in …

1999年1月1日 · Objective: To evaluate patterns of successful gait strategy in Huntington disease (HD) at various stages of illness to improve fall avoidance and maintenance of independence. Design: Repeated measurements of gait kinematic parameters and joint performance during gait cycles of six HD patients compared to 30 age-matched controls.

2020年2月11日 · Impaired gait plays an important role for quality of life in patients with Huntington’s disease (HD). Measuring objective gait parameters in HD might provide an unbiased assessment of motor deficits in order to determine potential beneficial effects of future treatments.

2023年8月10日 · Involuntary choreatic movements, bradykinesia and changes in footstep patterns associated with damage to the basal ganglia nuclei are common in people with Huntington’s disease (HD) [1,2]. Postural instability and cognitive changes may also contribute to altered gait

We investigated 13 patients with Huntington's disease and assessed gait by filming and by gait analyzer before and after increasing haloperidol dosage, until chorea was suppressed or side effects intervened. The severity of chorea and ataxia was scored blindly from videotapes.

2017年10月12日 · The gait pattern in HD is characterized by pathological, over-normative forward inclination of the trunk, resulting in the appearance of compensation patterns in the lower limbs. The upper segment of the body HAT (head, trunk, arms) represents about 62% of the total weight of the body above the pivot axis of the hip joint (Winter and Eng, 2013 ).

Disturbances of gait occur in all stages of Huntington’s disease (HD) including the premanifest and prodromal stages. Individuals with HD demonstrate the slower speed of gait, shorter...

Increased variability in step and stride length, slower walking velocity, increased stance phase, and decreased swing phase and single support time with preserved cadence suggest that HD gait patterns are slow, ataxic and ineffective. This study suggests that …