HER2 is a member of the human epidermal growth factor receptor (HER/EGFR/ERBB) family. But contrary to other members of the ERBB family, HER2 does not directly bind ligand. HER2 …

Human epidermal growth factor receptor 2 (HER2) is a member of the epidermal growth factor receptor family having tyrosine kinase activity. Dimerization of the receptor results in the …

人表皮生长因子受体-2（her2）在20世纪80年代被三个研究小组独立发现的，是迄今为止被研究的比较透彻的乳腺癌基因之一。her2基因是临床治疗监测的预后指标，也是肿瘤靶向治疗药物选 …

HER2（UniProt[1]: P04626），即人类 表皮生长因子受体 2（Human Epidermal Growth Factor Receptor 2），属于 受体酪氨酸激酶 家族的一员。在人体中，HER2主要参与细胞生长和分化 …

HER2 is a membrane tyrosine kinase and oncogene that is overexpressed and gene amplified in about 20% of breast cancers. When activated it provides the cell with potent proliferative and …

人类表皮生长因子受体2 （英語： human epidermal growth factor receptor 2， 缩写 为 HER2，亦称为 Neu 、 ErbB-2 、 CD340 （分化群 340）或 p185）是一种由 ERBB2 基因 编码的蛋白 …

Here I review the evidence supporting the oncogenic function of HER2, the mechanisms that are felt to mediate its oncogenic functions, and the evidence that links the experimental evidence …

Human epidermal growth factor receptor 2 (HER2) is a member of the epidermal growth factor receptor family having tyrosine kinase activity. Dimerization of the receptor results in the …

2007年4月30日 · Human epidermal growth factor receptor-2 (HER2) and neu are the human and rodent homologues of an oncogenic growth factor receptor that were identified and named...

HER2 is a highly specific and promising target for new breast cancer treatments. The recombinant human anti-HER2 monoclonal antibody (rhuMAb-HER2, trastuzumab, Herceptin) induces …