Glutamic acid (symbol Glu or E; [4] the anionic form is known as glutamate) is an α- amino acid that is used by almost all living beings in the biosynthesis of proteins. It is a non-essential …

Glutamate is synthesized in the central nervous system from glutamine as part of the glutamate–glutamine cycle by the enzyme glutaminase. This can occur in the presynaptic …

Glutamate synthesis and cycling between neurons and glia. The action of glutamate released into the synaptic cleft is terminated by uptake into neurons and surrounding glial cells via specific …

2022年12月19日 · Glutamate is the principal excitatory neurotransmitter of the central nervous system and the most abundant neurotransmitter in the brain. It is stored within vesicles in axon …

Glutamate is an amino acid transmitter and is the primary excitatory neurotransmitter in the brain. In the presynaptic terminal, glutamine is converted into glutamate via the enzyme glutaminase, …

2025年1月22日 · This detailed exploration delves into the intricate pathways and mechanisms responsible for glutamate synthesis. The Primary Pathway: The Glutamate-Glutamine Cycle. …

There is more glutamate per volume of brain tissue than any other neurotransmitter. In the presynaptic terminal, glutamine is converted into glutamate via the enzyme glutaminase, which …

2012年9月1日 · This brief review is focused entirely on the metabolic aspects of glutamate and GABA synthesis and neurotransmission. It describes in limited detail the synthesis, release, …

1998年1月1日 · Glutamate (Glu) is a key substance in the brain, being involved in metabolism, pathology, and neurotransmission and is an essential source of energy. It is involved in the …

2024年7月25日 · Glutamate metabolism, which to a large extent takes place in astroglial cells, is catalyzed either by glutamine synthetase or glutamate dehydrogenase. The neurotransmitter …