2025年1月10日 · Gene expression profiling tests, such as Oncotype DX, EndoPredict and MammaPrint, may help predict the risk of recurrence and give your doctor an idea of how your cancer cells might respond to chemotherapy. If it's not clear whether you'd benefit from chemotherapy, these tests can be helpful.

2024年4月23日 · Gene therapy is a promising treatment and a growing area of research. But its clinical use is limited today. In the U.S., FDA-approved gene therapy products include: Axicabtagene ciloleucel (Yescarta). This gene therapy is for adults who have certain types of large B-cell lymphoma that don't respond to treatment.

2024年12月20日 · Lymphoma is a cancer of the lymphatic system. The lymphatic system is part of the body's germ-fighting and disease-fighting immune system.

Pharmacogenomics, also called pharmacogenetics, is the study of how genes affect the body's response to medicine. The CYP450 tests look for gene changes, also called gene variations. Gene changes can affect how well a medicine may work for you. Tests also can show if a specific medicine is likely to cause side effects.

2024年4月9日 · In about 1 of every 5 breast cancers, the cancer cells have extra copies of the gene that makes the HER2 protein. HER2 -positive breast cancers tend to be more aggressive than other types of breast cancer.

2025年1月9日 · This gene controls the amount of iron the body absorbs from food. The altered gene is passed from parents to children. This type of hemochromatosis is by far the most common type. It's called hereditary hemochromatosis. Gene mutations that cause hemochromatosis. A gene called HFE is most often the cause of hereditary hemochromatosis.

2023年4月29日 · As gene research goes on, researchers are finding links between late-onset Alzheimer's and a number of other genes. Examples include: ABCA7. This gene seems to be linked to a greater risk of Alzheimer's disease. Researchers suspect that it may have something to do with the gene's role in how the body uses cholesterol. CLU.

2023年11月28日 · With one changed gene, you are a carrier and can pass the changed gene to your children. But they wouldn't develop the condition unless they also inherited a changed gene from their other parent. Risk factors. A child is at risk of MCAD deficiency if both parents are carriers of a gene known to cause it. The child then inherits two copies of ...

2022年5月13日 · In a person with PKU, a change in the phenylalanine hydroxylase (PAH) gene causes a lack of or reduced amount of the enzyme that's needed to process phenylalanine, an amino acid. A dangerous buildup of phenylalanine can develop when a person with PKU eats protein-rich foods, such as milk, cheese, nuts or meat, or grains such as bread and pasta ...

2021年6月30日 · Familial adenomatous polyposis (FAP) is a rare, inherited condition caused by a defect in the adenomatous polyposis coli (APC) gene. Most people inherit the gene from a parent. But for 25 to 30 percent of people, the genetic mutation occurs spontaneously. FAP causes extra tissue (polyps) to form in your large intestine (colon) and rectum.