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De-/protonation of R-OH group by acids and bases
2014年10月7日 · $\begingroup$ I don't think this is sufficient for a full answer, so I'll leave a comment. Re: your first statement, in order for the acid-base reaction to be product-favored, it is necessary that the pKa of the conj. acid be greater than the pKa of the acid on the reactant side.
extraction - Why is a weak base more able to deprotonate a …
2019年5月19日 · Apparently I am able to use sodium bicarbonate $(\ce{NaHCO3}),$ a weak base, as a way to deprotonate the stronger acid, carboxylic acid. This allows the carboxylic acid to dissolve into the aqueous phase in an ether extraction, as shown in the far left of the attached diagram, while the phenol would remain in the organic phase ( A at the bottom ...
organic chemistry - Do the amino groups in EDTA deprotonate …
2017年11月21日 · The carboxylates deprotonate first followed by the amines. The pKa values for the carboxylates ar 0.0, 1.5, 2.0, and 2.66. The amines have pKa values of 6.16 and 10.24. Ref. Harris. Quantitative Chemical Analysis.
Solved Deprotonate the most acidic hydrogen and draw the - Chegg
Draw the better contributing structure of the conjugate base. OH + H20 Create OscerSketch Answer 6 Using curved arrows, provide the mechanism illustrating the deprotonation performed in the previous problem that resulted in the conjugate base. You must draw out the hydrogen from the carbon you will deprotonate from. Do not draw the product.
Solved Which bases can deprotonate acetylene )= (25 ? The
Which bases can deprotonate acetylene )=(25 ? The conjugate acid products produced from the deprotonation of acetylene and their pKa values are given in parentheses. Check all that apply.)=CH2,pKa=(43)=(6.4)=(38None of the above
Can aniline autodeprotonate? - Chemistry Stack Exchange
However, the $\mathrm pK_\mathrm a$ of aniline is 27, which means, that it is, if at all, a very very poor acid, making it in my eyes impossible to deprotonate. Maybe it could be possible with n-BuLi, but that was not part of the reaction. The main topic was a nucleophilic aromatic substitution to 1-bromo-4-nitrobenzene, with aniline.
Solved Q 3.34: Identify a base that can be used to | Chegg.com
Question: Q 3.34: Identify a base that can be used to deprotonate propane (CH3CH2CH3) efficiently. А "NH2 B None of the given bases are suitable. HCEC E Q 3.33: Identify the most appropriate base to deprotonate the following compound: H A B None of the given bases are suitable. х с но" E
How does deprotonation works? - Chemistry Stack Exchange
2021年11月29日 · I've been studying organic chemistry and came across this example : CH3-CH2-CH(+)-CH3 ---> CH3-CH=CH-CH3, the explanation the textbook gave was related to deprotonation. I've tried drawing lewis
organic chemistry - Do Grignard reagents deprotonate amines ...
2016年4月12日 · Can I add Mg/dry ether to 2,4,6-tribromoaniline followed by $\\ce{D2O}$ in order to replace the bromines with deuterium? The reaction I'm proposing is part of a synthetic route as shown below.
Solved Select all bases that will deprotonate the following - Chegg
Select all bases that will deprotonate the following compound favorably. NaH NaOH CH3COOK CH3CH2CH2CH2Li (aka BuLi)A student wants to perform a reaction using hydronium (H3O+). Which of the following sets of reagents could the student …