2024年11月27日 · Studies have linked HMB to various health benefits, such as improved exercise adaptations, reduced muscle loss, better exercise recovery, and more.

HMB and a calcium salt of HMB (Ca-HMB) have most often been used by adults in doses of 2.4-3 grams by mouth daily. Speak with a healthcare provider to find out what type of product and dose...

Daily HMB supplementation (typically 3 g/day) is demonstrated to have an anti-catabolic effect, enhance protein synthesis, attenuate proteolysis, increase muscle mass, and decrease muscle damage in older adults [20, 24, 25].

2024年6月17日 · Several studies have reported multiple benefits of HMB supplementation on muscle performance, including increased aerobic activity, lean body mass, and ability to lift heavier weights. For...

In short, HMB works in two ways — increasing protein synthesis while decreasing protein breakdown.1 This combined anti-catabolic (anti-muscle protein breakdown) and anabolic (muscle protein building) impact means you build lean mass more efficiently – so, that’s greater gains in muscle and strength.2.

2020年8月28日 · In two randomized double-blind studies, Flakoll et al. found that daily supplementation with calcium HMB and two amino acids, arginine and lysine, (HMB/Arg/Lys) for 12 weeks significantly increased muscle strength and improved functionality and tended to enhance the gain of muscle mass; these effects were attributed to increased whole-body ...

2019年4月26日 · HMB has increased ATP (the cellular energy molecule), enhanced AMPK (a metabolic master switch), upregulated mitochondrial fitness, and supported better insulin signaling.* These are important goals of the formula.

2020年10月15日 · The primary aim of this study was to determine whether supplementation with calcium β-hydroxy-β-methylbutyrate (HMB) and vitamin D3 (D) would enhance muscle function and strength in older adults.

Furthermore, HMB is involved in the downregulation of NFkB and FOXO transcription factors, improves mitochondrial biogenesis, enhanced sarcoplasmic reticulum calcium release during exercise, and has been shown to stabilize cell membranes via cholesterol synthesis HMG-coenzyme A reductase.

2018年9月19日 · HMB has been shown in studies to stimulate muscle protein synthesis by sparking an increase in anabolic signaling through the mTOR pathway, and inhibit muscle protein breakdown by blunting catabolic signaling within the ubiquitin-proteasome pathway.