2023年11月29日 · What’s Lp (a)? Lp (a) is a genetically inherited lipoprotein and a common independent risk factor for heart disease. Lp (a) is made up of two major proteins: apolipoprotein (a) [apo (a)] and apolipoprotein B (apoB)-100.

Apolipoprotein A1 (ApoA1) is the primary protein associated with high-density lipoprotein (HDL) particles, and plays a central role in reverse cholesterol transport.

Apolipoprotein A-I (ApoA-I), the major protein component of high-density lipoproteins (HDL) is a multifunctional protein, involved in cholesterol traffic and inflammatory and immune response regulation.

Apolipoprotein A-I (apo A-I) an indispensable component and a major structural protein of high-density lipoprotein (HDL), plays a vital role in reverse cholesterol transport and cellular cholesterol homeostasis since its identification.

2000年6月1日 · The inverse relationship between high density lipoprotein (HDL) plasma levels and coronary heart disease has been attributed to the role that HDL and its major constituent, apolipoprotein A-I (apoA-I), play in reverse cholesterol transport (RCT).

The APOA1 gene provides instructions for making a protein called apolipoprotein A-I (apoA-I). ApoA-I is a component of high-density lipoprotein (HDL). HDL is a molecule that transports cholesterol and certain fats called phospholipids through the …

ApoA-I exerts its anti-inflammatory effects mainly by regulating the functions of immune cells, such as monocytes/macrophages, dendritic cells, neutrophils, and T lymphocytes. It also modulates the function of vascular endothelial cells and adipocytes.

2021年7月7日 · Apolipoprotein A-I (Apo-A1) is a structural and functional protein that constitutes approximately 70% of the protein in high density lipoprotein (HDL). The reference range of Apo-A1 varies by...

Apolipoprotein A-I (apo A-I) an indispensable component and a major structural protein of high-density lipoprotein (HDL), plays a vital role in reverse cholesterol transport and cellular cholesterol homeostasis since its identification.

Recent studies demonstrate that HDL apoA-I is an anti-inflammatory mediator modulating the progression of atherosclerosis through immune cell function. A direct link between immune cell function and lipoprotein metabolism was recently demonstrated when lymphotoxin and LIGHT produced by T cells were found to regulate plasma triglyceride levels 5.