Solid tumors are not simply clones of cancer cells. Instead, they are abnormal organs composed of multiple cell types and extracellular matrix. Some aspects of tumor development resemble …

2022年1月10日 · We see that evolutionarily novel organs such as the eutherian placenta, mammary gland, prostate, infantile human brain, and hoods of goldfishes have many features …

2010年6月15日 · Solid tumors are not simply clones of cancer cells. Instead, they are abnormal organs composed of multiple cell types and extracellular matrix. Some aspects of tumor …

2020年10月5日 · Innovations in biomaterials and stem cell technology have allowed for the emergence of novel three-dimensional (3D) tissue-like structures known as organoids and …

2022年4月8日 · Mammalian adipose is a tumor-like organ, and obesity is a tumor-like process. Thus, adipose, an evolutionarily young organ of mammals, shares many features with tumors. …

2022年1月10日 · It turns out that evolutionarily new organs such as the eutherian placenta, mammary gland, prostate, the infantile human brain, and hoods of goldfishes indeed have …

2024年3月27日 · Patient-derived tumor-like organs can be used to study tumorigenesis and metastasis, identify new prognostic biomarkers and screen drug candidates. Moreover, PDOs …

2019年9月3日 · Tumor-like lesions, such as hernias, are more common and must be distinguished from true tumors. Medical imaging is valuable for discovering, diagnosing, and …

2023年11月2日 · Most intriguingly, we found that tumor structures induced early in organoid culture tend to form more basal-like tumor structures, while later induction frequently formed …

2010年6月15日 · Understanding the complex ways in which cancer cells interact with their surroundings, both locally in the tumor organ and systemically in the body as a whole, has …