In this review, we discuss the pathophysiology, clinical presentation, prevention, and management of musculoskeletal complications of prolonged exposure to GCs. Any chronic excess of GCs, …

Occasional fibers undergoing degeneration and scattered atrophic fibers have been described in muscle biopsy specimens. 1,3,4 In this paper, histochemical studies of affected muscle in two …

Glucocorticoid-induced myopathy with self-reported muscle weakness is present in up to 60% of patients with florid Cushing’s syndrome (CS). It is reported to be more frequent in men than in …

Nearly 60% of patients with Cushing's syndrome have muscle weakness. Glucocorticoid-induced muscle atrophy affects mainly fast-twitch glycolytic muscle fibers (type IIb fibers). This brief …

2017年6月22日 · Cushing syndrome (CS) is a constellation of clinical signs and symptoms resulting from chronic exposure to excess cortisol, either exogenous or endogenous. …

Prolonged exposure to an excess of glucocorticosteroids (GCs), both endogenous and exogenous, leads to a wide range of comorbidities, including cardiovascular, metabolic, …

2020年9月30日 · People with Cushing’s syndrome experience muscle weakness that persists even when the disorder is in remission, a new study shows. The study, “ Persisting muscle …

2017年6月1日 · Skeletal muscle wasting occurs in pathophysiological response to Cushing's syndrome. The forkhead box (FOX) protein family has been implicated as a key regulator of …

Cushing’s syndrome is a general term for increased secretion of cortisol by the adrenal cortex. When corticosteroids are administered externally, a condition of hypercortisolism called …

Surgical remission of Cushing syndrome is the most important step for recovery of muscle function. Restoration depends on age, co-morbidities and postoperative insulin-like growth …