2024年6月1日 · Perfusion weighted imaging is a term used to denote a variety of MRI techniques able to give insights into the perfusion of tissues by blood. There are three techniques in wide use to derive one or more perfusion values: techniques. dynamic …

Perfusion MRI or perfusion-weighted imaging (PWI) is perfusion scanning by the use of a particular MRI sequence [which?]. The acquired data are then post-processed to obtain perfusion maps with different parameters, such as BV (blood volume), BF (blood flow), MTT (mean transit time) and TTP (time to peak).

In this article, we will address five ques-tions that radiologists and radiographers fre-quently ask when planning, performing, pro-cessing, and interpreting different perfusion MRI studies in diseases of the CNS.

2024年10月13日 · Dynamic susceptibility contrast (DSC) MR perfusion is one of the most frequently used techniques for MRI perfusion, and relies on the susceptibility induced signal loss on T2*-weighted sequences which results from a bolus of gadolinium-based contrast passing through a capillary bed.

Dynamic perfusion MR imaging data analyzed using the radiotracer kinetic theory yields quan-titative estimates of cerebral blood volume that reflect the underlying microvasculature and an-giogenesis.

Perfusion MRI is a promising tool in assessing stroke, brain tumors, and neurodegenerative diseases. Most of the impediments that have limited the use of per-fusion MRI can be overcome to allow integration of these methods into modern neuroimag-ing protocols.

2018年11月8日 · Perfusion imaging with magnetic resonance imaging (MRI) is possible with many different tracers. Because unusual nuclear species are readily detected in the body with MRI, a number of investigations using fluorinated compounds (4,5,6), deuterated water , and O 17 have been performed.

MR perfusion is a specialized MR technique that evaluates the relative perfusion tissue. Most of the time this is done in association with contrast enhancement but future techniques are promising for the possibility of being able to do it without contrast enhancement.

The ultimate goal of perfusion MRI is to measure or assess the blood flow irrigating the explored organ, expressed in milliliters per 100 gram of tissue per minute. This flow corresponds to microcirculatory tissue perfusion rather than the flow of the main vascular axes.

In this section, we outline the principles of MR-based perfusion imaging with respect to different contrast mechanisms based on the manipulation of the longitudinal (T1) and transverse relaxation times (T2, T2*) as well as the implications of exogenous and endogenous contrast agent.