Patients With HER2+ Breast Cancer Who Achieve pCR With
2022年2月9日 · Patients with HER2-positive, early-stage breast cancer who achieved a pathologic complete response (pCR) after receiving HER2-targeted therapy experienced …
乳腺癌患者中20%~30%人表皮生长因子受体2(human epidermal growth factor receptor 2,HER2)阳性,该类型乳腺癌具有恶性程度高、侵袭性强、预后差等特点。 抗HER2靶向药物能有效地降 …
pCR Further Validated as Predictor of Outcomes in HER2+ Breast …
2022年3月23日 · Pathologic complete response rate (pCR) was further validated as a predictor of outcomes in patients with HER2-positive breast cancer, particularly those who are hormone …
Her2 assessment using quantitative reverse transcriptase …
Immunohistochemistry (IHC) and fluorescent-in situ hybridization (FISH) are standard methods to assess human epidermal growth factor receptor 2 (HER2) status in breast cancer (BC) …
文献解读｜乳腺癌中 HER2 拷贝数变异的数字 PCR 方法的建立和 …
2023年1月15日 · 本文的目的是开发高度准确和灵敏的dPCR检测方法，以检测HER2的拷贝数浓度，探索确定HER2 CNV的潜在新参考基因，检测常见参考基因CEP17的适用性，以及通过检 …
Quantitative RT-PCR assay of HER2 mRNA expression in formalin …
Molecular techniques based on the quantitative evaluation of HER2 messenger RNA (mRNA) have been proposed. Especially, a reverse transcription quantitative PCR (RT-qPCR) was …
Quantitative real-time RT-PCR and chromogenic in situ …
To elucidate the molecular profile of HER-2 status, mRNA and protein expression in 75 invasive breast carcinomas were analyzed by real time quantitative RT-PCR (qRT-PCR) and IHC, …
Establishment and evaluation of digital PCR methods for HER2 …
Accurate measurement of human epidermal growth factor receptor 2 (HER2) copy number variation (CNV) is very important for guiding the tumor target therapy in breast cancer. Digital …
Using digital PCR to detect HER2 amplification in breast and gastric ...
2018年9月1日 · Here we report the development and validation of a digital PCR based assay to be used to determine the status of HER2 amplification in both tissue and plasma samples. …
Detection of HER2 Gene Polymorphism in Breast Cancer: PCR …
2016年2月14日 · In this study we applied allele-specific PCR to discriminate each allelic type of HER2 in breast cancer patients in a simple way using fragment sizes-based agarose …