The exosome journey: from biogenesis to uptake and intracellular ...
Exosomes are small extracellular vesicles secreted by all cell types playing intercellular communication roles in health and disease by transferring cellular cargoes such as functional …
The biology, function, and biomedical applications of exosomes
Exosomes: A cell-to-cell transit system in the human body with pleiotropic functions. Exosomes are extracellular vesicles generated by all cells and they carry nucleic acids, proteins, lipids, …
The Machinery of Exosomes: Biogenesis, Release, and Uptake
Exosome biogenesis pathway is initiated by endocytosis of molecular cargo into the cell. Early endosome, the initial vesicle generated by the plasma membrane budding into the cell, is the …
Exosomes: Large-scale production, isolation, drug loading …
2022年7月1日 · Exosomes released by antigen-presenting cells (APCs), for example, can express MHC class I and II molecules, which aid CD8+ and CD4+ T cells in inducing distinct …
Specificities of secretion and uptake of exosomes and other ...
2019年1月2日 · The ability of exosomes to transfer cargo from donor to acceptor cells, thereby triggering phenotypic changes in the latter, has generated substantial interest in the scientific …
Current knowledge on exosome biogenesis and release
2017年7月21日 · Exosomes are isolated from cell-conditioned media by several protocols that aim to concentrate the exosomal signal to be analyzed and to avoid contaminating molecules such …
Exosomes and Ectosomes in Intercellular Communication - Cell …
2018年4月23日 · Exosomes and ectosomes, two distinct types of extracellular vesicles generated by all types of cell, play key roles in intercellular communication. The formation of these …
Exosomes: a review of biologic function, diagnostic and targeted ...
2024年7月11日 · Exosomes are extracellular vesicles generated by all cells and they carry nucleic acids, proteins, lipids, and metabolites. They mediate the exchange of substances between …
The ins-and-outs of exosome biogenesis, secretion, and ... - Cell …
2023年7月26日 · Exosomes are secreted both as individual structures that diffuse into the extracellular environment and as clusters that remain attached to the PM of donor cells. …
Harnessing the power of exosomes for diagnosis, prognosis, and ...
2025年1月7日 · Exosomes are small extracellular vesicles of endocytic origin released by various cell types. They consist of lipid bilayers containing macromolecules such as lipids, proteins, …