D50%W, such as improperly placing the IV and or rapidly administering dextrose, has been associated with extravasation. Dextrose 50% is a hyperosmolar solution at 2520 mOsm/kg,

Treatment for significant hypoglycemia includes administration of dextrose containing agents, including 50% dextrose (D50%W) intravenously. Significant extravasation of D50%W can lead to complications, including skin and soft tissue injury, loss of limb, or death.

Intravenous catheter malfunction causing extravasation is a common occurrence in the emergency department (ED). A 17-year-old girl who had a syncopal episode was given an ampule of dextrose 50% water into her antecubital region by emergency medical services.

2021年10月4日 · D50 must be pushed as an injection, which can sometimes be difficult, especially through a smaller caliber IV catheter. D10 can be run wide open as a bolus of 250 mL over however long it takes to infuse.

2016年9月6日 · This case illuminates a severe medical complication of extravasation of D50 that led to an acute compartment syndrome and required an emergent operative intervention. It is the first prehospital case of dextrose extravasation leading to a compartment syndrome.

2025年1月2日 · However, it’s important to note that one amp of D50 should be infused over 2-3 minutes to avoid extravasation. Studies show that a 200mL bolus of D10 (containing 20g of glucose) can be administered via pressure bag and will enter the patient’s bloodstream as quickly as slow pushing an amp of D50 (containing 25g of glucose).

It is the first documented case of prehospital dextrose extravasation leading to compartment syndrome. There may be safer alternatives to D50 administration and providers must be acutely aware to monitor for D50 infusion complications.

D50 is well known to cause phlebitis and local skin necrosis as a complication. This case illustrates the danger of compartment syndrome after D50 extravasation. It is the first documented case of prehospital dextrose extravasation leading to compartment syndrome.

2013年4月17日 · Treatment for significant hypoglycemia includes administration of dextrose containing agents, including 50% dextrose (D50% W) intravenously. Significant extravasation of D50% W can lead to...

2013年4月23日 · Treatment for significant hypoglycemia includes administration of dextrose containing agents, including 50% dextrose (D50%W) intravenously. Significant extravasation of D50%W can lead to complications, including skin and soft tissue injury, loss of limb, or death.