The cardiac OFT, comprised of the conus or bulbus cordis and the truncus arteriosus (together called the conotruncal region), is a rapidly remodeling structure during embryogenesis at the arterial pole of the heart, as it connects the embryonic ventricles to the aortic sac [3].

2024年1月19日 · However, if tetralogy of Fallot is to be considered a conotruncal anomaly, then so should the so-called Eisenmenger ventricular septal defect. So, arguably, should all of the ventricular septal defects associated with malalignment of the outlet septum.

septum (Figure 1, C). The septum is a protrusion that has grown from the dorsal wall of the aortic sac.7 During the same period, the more proximal parts of the outflow tract, which have retained their myocardial walls, are separated intoaorticandpulmonarychannelsbytheformationofcush-ions.Bythemiddleofthesixthweekofdevelopment,atCar-

2018年10月19日 · 圆锥动脉干畸形 (conotruncal defects，CTD)是胚胎期心球段即圆锥动脉干段发育过程受到干扰或发育停顿所致，包括法洛四联症 (Tetralogy of Fallot, TOF)、肺动脉闭锁伴室间隔缺损 (pulmonary atresia with ventricular septal defect, PA/VSD)、完全性大动脉转位 (complete transposition of great arteries, D-TGA)、右室双出口 (double outlet right ventricle, DORV)、永存动脉干 (persistent truncus arteriosus, PTA)等，约占青紫型先心病的7O％，近半数可死于婴儿期。

At this stage, the heart is partially partitioned by the primitive atrial septum (PAS), interventricular septum (IVS) and atrioventricular cushions (AV cushions) into a prototypic four-chamber heart. The AVC is divided into tricuspid and mitral orifices, forming ventricular inlets that connect the respective atrium to the ventricle.

septum creates the ascending aorta and pulmonary trunk (Fig. 7-6B). b) Septum formation in the conus cordis (outflow tracts from the ventricles) and formation of the conotruncal septum. Two conus swellings (Fig. 7-2), also referred to as bulbar ridges (Fig. 7-7B), appear on opposite walls of the conus cordis just inferior to the truncus swellings.

The apical aspect of the ventricular septum (muscular septum) accrues as the ventricles balloon out from the primitive heart tube. The primary ring tissue between the expanding ventricles is a primitive heart tube and grows very little; thus, as the chambers expand apically, the septum develops between the expanding ventricles.

2015年12月20日 · Conotruncal anomalies are a group of congenital heart defects involving the outflow tract of the heart and great vessels. The conotruncal anomalies include tetralogy of Fallot (TOF), transposition of the great arteries (TGA), double-outlet ventricles, and truncus arteriosus.

2022年6月30日 · Conotruncal anomalies, also referred to as outflow tract anomalies, are congenital heart defects that result from abnormal septation of the great vessels’ outflow tracts. The major conotruncal anomalies include tetralogy of Fallot, double-outlet right ventricle, transposition of the great arteries, truncus arteriosus, and interrupted aortic arch.

2016年3月30日 · The left extremity of the VIF represents the upper part of the ventricular septum: the outlet (or conal) septum (asterisk), which is fused with the upper extremity of the septal band (SB, or septomarginal trabeculation), between its two limbs, anterior (AL) and posterior (PL).