The diagnosis of conjunctival stromal tumor describes a CD34-positive benign mesenchymal tumor with matrix varying from purely myxoid to purely collagenous. Differential diagnosis is broad ranging from fibroxanthomatous lesions to scar.

2011年6月18日 · Four patients with a conjunctival lesion that were classified histologically as low-grade stromal tumors consisting of spindle-shaped cells with occasional pseudonuclear inclusion and multinucleated cells in a partly myxoid matrix.

We propose to classify these benign lesions, which share distinct histopathologic features, as "conjunctival stromal tumors." A reactive/inflammatory component needs to be considered in the pathogenesis of this lesion.

2019年3月26日 · This chapter describes benign and malignant tumors of the conjunctival stroma according to their tissue of origin: vascular and lymphatic tumors, fibrous tumors, histiocytic tumors, myxoid tumors, myogenic tumors, choristomas, and metastatic and secondary tumors.

2024年3月1日 · Histopathological assessment showed a paucicellular tumour set in an oedematous and collagenous background within the lamina propria. Significant nuclear degenerative atypia was noted. Lesional cells were positive for CD34 immunohistochemistry. The features were consistent with COST.

Benign conjunctival tumors include congenital, melanocytic, epithelial and stromal lesions. Clinical observation often fails to make the diagnosis, and complete excisional biopsy must be performed as soon as growth is suspected. Histology remains the …

Histologically, we found abundant alcian blue positive extracellular substance with cells of various sizes containing one or multiple small spindle shaped nuclei and vacuolated cytoplasm, which also stained positive for alcian blue. Immunohistochemical stains …

Four cases of low-grade conjunctival stromal tumors were retrospectively identified in an oph-thalmic pathology laboratory database. Patients’ records were analyzed for demographic data, clinical appear-ance, and the postoperative course.

Conjunctival stromal tumour (COST) is a rare benign tumour arising from mesenchymal cells.1 There is a wide array of clinical appearances. While the distribution of COST is either localized or diffuse, its color ranges from red to yellow to white, and its physical description can vary from a cystic lesion, to a nodule, to a fibrovascular ...

2021年5月1日 · Conjunctival stromal tumor (COST) is an emerging entity with only a limited number of cases reported in the literature. In this report, we describe 2 additional cases, review the accumulative clinical and histopathological features and expand on the immunophenotypic property of this entity.