While in-hospital mortality rates can be greater than 25–30% across resource settings, mortality rates of up to 38% are reported in LMICs, particularly in patients who have confirmed bacteremia [1, 3, 5]. In Uganda, a low-income country in sub-Saharan Africa (SSA), the primary causes of death are all infectious in nature–namely malaria, HIV ...

20% of all deaths worldwide are associated with sepsis. Depending on country, mortality varies between 15 and more than 50 %. Many surviving patients suffer from the consequences of sepsis for the rest of their lives. At least 2 million sepsis deaths …

2019年6月11日 · We found pooled in-hospital mortality of 19% (95% CI 12–29%) for Sepsis-2-defined sepsis and 39% (95% 30–47%) for Sepsis-2-defined severe sepsis. Pooled 28-/30-day Sepsis-2-defined severe sepsis mortality was 54% (95% CI 37–70%).

2023年9月1日 · Based on the sub-group analysis, the pooled hospital-wide prevalence of sepsis in East and Southern Africa was 18% (95% CI: 11–25%), and 20% (95% CI: 2–42%), respectively. The pooled prevalence in the ICU was 14% (95% CI: 4–23%) and 13% (95% CI: 5–20%) for East and Southern Africa, respectively.

Five studies in the ICUs presented a pooled prevalence and mortality of 31% (95% CI: 24-38%) and 46% (95% CI: 39-54%), respectively. Based on the sub-group analysis, the pooled hospital-wide prevalence of sepsis in East and Southern Africa was 18% (95% CI: 11-25%), and 20% (95% CI: 2-42%), respectively.

Global Sepsis Mortality Rates from 1990–2017 The burden is especially high in sub-Saharan Africa Kristina E Rudd, Sarah Charlotte Johnson, Kareha M Agesa, et al. Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study. The Lancet; January 2020

2022年5月11日 · Results: Overall, 48,653 patient visits from 2010-2019 yielded 17,490 encounters for patients age≥18 who had suspected infection, including 10,437 with sepsis. The annual proportion of patients with sepsis decreased from 45.0%% to 21.3% and the proportion with malarial sepsis decreased from 17.7% to 2.1% during the study period.

• The majority (85%) of sepsis-related deaths occur in low- to middle-income countries. The highest sepsis burden is found in sub-Saharan Africa. • There are more deaths from sepsis than from cancer globally each year (11 million vs 9.6 million cancer deaths).6 Burden of Sepsis Among Medicare Beneficiaries2-4 Critical Facts

2021年12月6日 · Almost fifty million people worldwide develop sepsis every year, resulting in eleven million deaths annually. About 85% of cases occur in low and middle income countries such as countries in Africa. In addition, children (especially new borns), pregnant women and the elderly are the most affected.

2024年2月1日 · Five studies in the ICUs presented a pooled prevalence and mortality of 31% (95% CI: 24–38%) and 46% (95% CI: 39–54%), respectively. Based on the sub-group analysis, the pooled hospital-wide prevalence of sepsis in East and Southern Africa was 18% (95% CI: 11–25%), and 20% (95% CI: 2–42%), respectively.