We report on the development of the Respimat ® soft mist inhaler (SMI) and compare key attributes with metered-dose inhalers (MDIs) and dry powder inhalers (DPIs). The Respimat SMI, a pocket-sized device generating a single-breath, inhalable aerosol, was designed to enhance drug delivery to the lungs, reduce the requirements for patient ...

According to a LinkedIn post by generic device maker Merxin, the FDA has indicated that Merxin’s MRX004 soft mist inhaler is suitable for an ANDA submission for a generic version of Boehringer Ingelheim’s Spiriva Respimat tiotropium bromide SMI.

2023年3月31日 · Inhalers and nebulizers both deliver medicines that treat lung conditions. But an inhaler is a handheld device that doesn’t need electricity. It usually delivers dry powder or a spray of medication, though some use a soft mist of liquid medication. Nebulizers are larger and use a battery or you plug them in. You use them with a mask or ...

Generic Soft Mist Inhaler · Singmed’s self-developed soft mist devices (loaded with Tiotropinm Bromide Spray produced by Boehringer-ingelheim) have passed Bioequivalence Evaluation in 2021, allowing for the replacement of the novel product (Spiriva® Respimat®).

We design and supply dry powder and soft mist inhalers for clinical evaluation through to commercial supply. Our expertise encompasses various therapeutic categories, from biologics and small molecules to generic and novel therapies.

Generic Soft Mist Inhaler · 新劢德自主研发的柔雾装置已于2021年通过生物等效性评估，实现了对原研产品的可替代。 · 口袋大小的装置设计，能够产生一次呼吸可吸入的气雾，旨在增强药物输送到肺部的效率，减少患者协调和吸气力度的要求，并改善患者的使用体验 ...

2023年7月10日 · Soft mist inhalers (SMIs) are propellant-free inhalers that utilize mechanical power to deliver single or multiple doses of inhalable drug aerosols in the form of a slow mist to patients.

RESPIMAT is an inhaler device from the Boehringer Ingelheim respiratory product family, designed to generate a propellant-free mist-like cloud of medicine. The device is activated by a dose-release button designed to release one puff of medication independent of inspiration.

2004年9月28日 · Respimat ® Soft Mist ™ Inhaler (SMI) is a new generation inhaler that uses mechanical power from a spring rather than liquid-gas propellant to generate an aerosol cloud suitable for inhalation. This article reviews the development of Respimat ® SMI and describes how the latest advances in aerosol technology have been used in order to ...

Introduction: Soft mist inhalers (SMIs) are propellant-free inhalers that utilize mechanical power to deliver single or multiple doses of inhalable drug aerosols in the form of a slow mist to patients. Compared to traditional inhalers, SMIs allow for a longer and slower release of aerosol with a smaller ballistic effect, leading to a limited ...