welcome. Rosetta design can be used to identify sequences compatible with a given protein backbone. Some of Rosetta design's successes include the design of a novel protein fold, …

The energies, structure and sequence output by RosettaDesign are placed in a pdb file. The pdb file has the following sections: 1) coordinates of the design structure 2) a table of energies for …

Rosetta Protein Design. The Increase Affinity protocol is based on the premise that increasing buried hydrophobic surface area and/or decreasing buried hydrophilic surface area will …

CSV input instructions. To use the "comma separated value" (CSV) format simply pasted your comma-delimited data in the textbox. The input text must take the same form as the manual …

This file specifies which residues will be varied during the design run. Below is an example resfile which performs design at a subset of positions and repacking everywhere else.

The purpose of Scaffold Select is to help identify proteins that would make good scaffolds for the design of epitope-binding proteins. The protocol performs searches through a protein-peptide …

Please fill out the form below to submit a design job. Note: This server will design at most 200 positions. If your PDB file contains more than 200 residues, you must upload a resfile (see …

Adding diverse noncanonical backbones to rosetta: enabling peptidomimetic design. Drew K, Renfrew PD, Craven TW, Butterfoss GL, Chou FC, Lyskov S, Bullock BN, Watkins ...

Rosetta Commons Developers Participation Agreement ...

Rosetta Protein Design. Adding diverse noncanonical backbones to rosetta: enabling peptidomimetic design.