2016年1月5日 · Normal bladder filling has little or no change in pressure and no involuntary phasic contractions occur despite provocation. Normal voiding is achieved by a voluntarily initiated continuous detrusor contraction that leads to complete bladder emptying within a normal time span, and in the absence of obstruction

2023年8月14日 · Urodynamic testing is a collaborative and dynamic investigation involving both the patient and clinician and should incorporate clear communication and open cooperation. Standard urodynamic testing is performed in patients with LUT symptoms (LUTS). It involves noninvasive uroflowmetry, followed by invasive cystometry and a pressure-flow study.

2023年5月1日 · By adulthood, the average volume that a functional bladder can comfortably hold is between 300 and 400 mL. [10] . As the volume of urine held by the bladder increases, so too does the pressure therein. Wall pressure of 5 to 15 mm Hg creates a sensation of bladder fullness while 30 mm Hg and beyond is painful. [11] .

Normal human bladder contraction is mediated mainly through stimulation of muscarinic receptors in the detrusor muscle. The muscarinic receptors found in the human detrusor are of the M2 and M 3 subtypes [9–12].

2024年11月23日 · A normal bladder maintains an intravesical pressure of 20 cm H 2 O or less during filling until it reaches fullness or contracts. This ability of the bladder to manage increasing amounts of urine without increasing pressure is called compliance.

The normal bladder has storage and voiding phases, the onset of the latter being determined by the pontine micturition centre in the brainstem. Clinical problems affecting urine storage are highly prevalent, and result in urinary urgency, frequency and urgency incontinence.

2016年3月30日 · The normal bladder capacity is 400–500 ml in normal adults, although the bladder may expand significantly particularly in patients with atonic bladders. Table 1 describes the physiological parameters of the normal bladder.

Since its first publication in 1990, the IT has challenged the general view that the pathogenesis of overactive bladder (OAB) (urge, frequency, nocturia) is unknown and there is no cure. According to the IT, normal function bladder control is binary, either closed or open.

Normal bladder function is complex, resulting from the co-operative interaction of numerous regulatory cell types, of which the interstitial cells and the peripheral neurones are particularly interesting. Collectively, these comprise the myovesical plexus, which appears to …

2016年7月20日 · Bladder contracture is the end stage of chronic inflammatory disorders of the bladder or results from the treatment of carcinoma such as post radiotherapy. The chronic fibrotic damage to the bladder causes the bladder function to deteriorate severely.