Diabetic macroangiopathy, a prevalent and severe complication of diabetes mellitus, significantly contributes to the increased morbidity and mortality rates among affected individuals. This complex disorder involves multifaceted molecular mechanisms ...

In macroangiopathy, atherosclerosis and a resultant blood clot forms on the large blood vessels, sticks to the vessel walls, and blocks the flow of blood. Macroangiopathy in the heart is coronary artery disease; in the brain, it is cerebrovascular disease.

Here, we review recent knowledge of cellular and molecular pathways of macrovascular disease related to hyperglycemia in diabetes. We also here highlight how new insights into pathogenic mechanisms of vascular damage in diabetes may indicate new …

2018年5月23日 · Diabetic peripheral angiopathy is of two types: Macroangiopathy and microangiopathy. In macroangiopathy, blood clots are formed in large blood vessels such as the arteries and veins. This causes blockage to the flow of blood. It results in heart attack and stroke.

Microvascular and macrovascular vasculopathies as complications of diabetes can accentuate the onset of organ illnesses, thus it is imperative that research efforts help identify more effective methods for prevention and diagnosis of early vascular injuries.

2023年4月10日 · Diabetic panvascular disease (DPD) is a clinical syndrome in which vessels of various sizes, including macrovessels and microvessels in the cardiac, cerebral, renal, ophthalmic, and...

1996年7月1日 · In the present study, we have compared and analyzed published data related to the pathogenesis of the large vessel disease in diabetes. The prevailing opinion appears to be that diabetes accelerates the mechanism that leads to development of classical atherosclerosis.

2024年9月16日 · Diabetic macroangiopathy is a leading cause of diabetes-related mortality worldwide. Both genetic and environmental factors, through a multitude of underlying molecular mechanisms, contribute to the pathogenesis of diabetic macroangiopathy.

2024年2月2日 · Diabetic macroangiopathy, a prevalent and severe complication of diabetes mellitus, significantly contributes to the increased morbidity and mortality rates among affected individuals.

Macroangiopathy: A disease of the large blood vessels in which fat and blood clots build up and stick to the vessel walls, blocking the flow of blood. Types of macroangiopathy include coronary artery disease (macroangiopathy in the heart), cerebrovascular disease (macroangiopathy in the brain), and peripheral vascular disease (macroangiopathy ...