HLA variation and disease | Nature Reviews Immunology
2018年1月2日 · We evaluate the scope for personalized antigen-specific disease prevention, whereby harnessing HLA–ligand interactions for clinical benefit is becoming a realistic …
免疫系统之 HLA 与MHC - 知乎 - 知乎专栏
人类白细胞抗原（英语：human leukocyte antigen）- HLA是在 6号染色体短臂 上的一类基因，编码MHC蛋白质。HLA有不同的基因座，编码两大类 MHC蛋白 。 HLA高度多态性，同一种基 …
Human Leukocyte Antigen (HLA) System: Genetics and …
The human leukocyte antigen (HLA) system is one of the most crucial host factors influencing disease progression in bacterial and viral infections. This review provides the basic concepts …
人類白細胞抗原 - 维基百科，自由的百科全书
人類白細胞抗原 （英語： human leukocyte antigen， 缩写 为 HLA），是編碼人类的 主要组织相容性复合体 （MHC）的基因。 其位于 6号染色体 的短臂上（6p21.31），包括一系列紧密连 …
The HLA genomic loci map: expression, interaction, diversity and ...
2009年1月9日 · The human leukocyte antigen (HLA) super-locus is a genomic region in the chromosomal position 6p21 that encodes the six classical transplantation HLA genes and at …
Major histocompatibility complex: Antigen processing and …
2013年7月18日 · The main function of HLA class I gene products (HLA-A, -B, and -C) is to present endogenous peptides to responding CD8+ T Cells while the class II coded molecules …
The HLA System: Genetics, Immunology, Clinical Testing, and …
The human major histocompatibility complex HLA is located on the short arm of chromosome 6. It is known to be the most polymorphic genetic system in humans. The biological role of the HLA …
Association of HLA-A and Non-Classical HLA Class I Alleles
2016年10月4日 · A complete Human Leukocyte Antigen (HLA) match is associated with better long term survival in transplant patients, however the effects of HLA-A, -B and -DRB1 …
Nature重磅！困扰科学界50年的谜题被解开，新方法发现自身免疫 …
人类白细胞抗原（Human Leukocyte Antigen, HLA）蛋白家族参与帮助免疫细胞检测入侵病原体并区分微生物和人类蛋白，并且HLA基因在个体之间差异极大。 而自身免疫性疾病通常被认为 …
Tutorial: a statistical genetics guide to identifying HLA alleles ...
2023年7月26日 · We provide detailed guidance on performing standard quality control measures for input genotyping data and describe options to impute HLA alleles and amino acids either …