Spinal stenosis is a narrowing of the spinal canal that causes compression of the spinal cord and/or nerve roots. Resulting pain and numbness (in the hands, arms, legs, and/or feet) can vary depending ...

Scientists have long observed a connection between opioid use disorder (OUD ... a process in the brain and spinal cord called central sensitization. Central sensitization is a condition where ...

is a common neurological test that's done to examine the cerebrospinal fluid (CSF)—the protective fluid that surrounds your brain and spinal cord. During the procedure, a needle is carefully inserted ...

The kappa opioid receptor was cloned in 1993 (Meng et al., 1993), while its pharmacological identification spans more than two-decades before. Portoghese and others proposed more than a single opioid ...

This study aimed to assess the differential expression of opioid receptors between healthy and tumor tissues in patients with stage II and III colorectal cancer undergoing elective surgery by ...

“Perioperative pregabalin does not reduce postoperative opioid consumption or the incidence of persistent postoperative pain following instrumented posterior spinal fusion for spinal deformities in an ...

All these effects are mediated by the interactions of opioids with members of the opioid receptor family ... into different areas of the brain or spinal cord. Thus pharmacological evidence ...