Mapping the key signaling molecules in biochemical pathways will be central to future drug discovery efforts. Signal transduction describes the process of conversion of external signals ...

This omega-6 fatty acid, arachidonic acid, is an important starting material for three different types of signaling molecules (Figure 3). Similar research found pathways that converted fat from ...

New research shows that a network of subcellular structures similar to those responsible for propagating molecular signals ...

Pharmaceutical ads are difficult to avoid in American television programming and a growing number of them promote a class of medications called JAK inhibitors, using an acronym that assumes the ...

We use high resolution live imaging, synthetic biology and biochemistry to figure out when and where signaling molecules are activated to make these essential decisions. We are motivated by re-wiring ...

Our longstanding interest is the global and comprehensive understanding of how key cellular signaling molecules; protein kinases, protein phosphatases and transcription factors mediate their signaling ...

Our cells use oxygen to generate energy by burning nutrients to keep various processes in the cell working. While making this energy in the mitochondria (the cell’s power plants), the cell also ...