Mapping the key signaling molecules in biochemical pathways will be central to future drug discovery efforts. Signal transduction describes the process of conversion of external signals ...

This omega-6 fatty acid, arachidonic acid, is an important starting material for three different types of signaling molecules (Figure 3). Similar research found pathways that converted fat from ...

New research shows that a network of subcellular structures similar to those responsible for propagating molecular signals ...

We use high resolution live imaging, synthetic biology and biochemistry to figure out when and where signaling molecules are activated to make these essential decisions. We are motivated by re-wiring ...

Our longstanding interest is the global and comprehensive understanding of how key cellular signaling molecules; protein kinases, protein phosphatases and transcription factors mediate their signaling ...

Interferons are signaling molecules that are released by cells in response to viral infections, immune responses, and other ...

"This enabled us to visualize the signaling molecules and the biochemical processes in which they are involved in individual cells and observe them in real time, at work so to speak," says Lehners.

Our cells use oxygen to generate energy by burning nutrients to keep various processes in the cell working. While making this energy in the mitochondria (the cell’s power plants), the cell also ...