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自噬:癌症的双刃剑——从抑制到促进,探索自噬在肿瘤发生与进展 ...
考虑到自噬在癌症生物学中的关键作用,它成为癌症治疗的新靶点。 1. 纳米受体通过模拟选择性自噬受体促进突变型p53蛋白降解 在一些癌症中,突变型p53促进肿瘤的发生、发展、转移和耐药性,靶向蛋白质降解被视为一种有效的治疗策略。然而,缺乏特定的自 ...
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