Due to proteostasis stress induced by aging or disease, misfolded proteins can form toxic intermediate species of aggregates and eventually mature into less toxic inclusion bodies (IBs). Here, using a ...

Researchers say CSF biomarker test correlates with the severity of cognitive decline, independent of other factors, including brain amyloid deposition.

Years before tau tangles show up in brain scans of patients with Alzheimer's disease, a biomarker test developed at the ...

Years before tau tangles show up in brain scans of patients with Alzheimer's disease, a biomarker test developed at the ...

Three more deer have tested positive for chronic wasting disease in Louisiana, one of them in St. Landry Parish, officials ...

In a novel theory, scientists at Arizona State University's Biodesign Institute propose a unifying explanation for the ...

Scientists are testing an experimental anti-amyloid antibody in people expected to develop early-onset Alzheimer's.

The sabotage of cellular messaging, triggered by the formation of chronic stress granules in the brain, may be a key factor ...

A new study has identified an enzyme that plays an important role in breaking down unneeded or damaged proteins in the heart -- an important process for maintaining heart health.

A new study has identified an enzyme that plays an important role in breaking down unneeded or damaged proteins in the heart – an important process for maintaining heart health.

Lewy body diseases (LBDs) are a class of debilitating neurodegenerative disorders linked to the abnormal aggregation of the ...