2008; Russell et al., 2010). M. tuberculosis can reside in macrophages, and avoid elimination by inhibiting the acidification of phagocytotic vesicles or by other means (Gengenbacher and Kaufmann, ...

Because immune cell metabolism and function are inextricably connected, addressing the different metabolic pathways of macrophages could provide a unique opportunity to modify its phenotype and ...

Apoptosis and autophagy constitute the two self-destructive processes by which supernumerary, damaged or aged cells and organelles are eliminated. Beyond this homeostatic function, autophagy is ...

Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical studies have implicated macrophage-mediated immune tolerance. Hence, pathways ...

Recycling takes place in our cells at all times: in a process called autophagy, cell components that are no longer needed are enclosed by membranes and broken down into their basic building blocks.

School of Clinical Medicine, Guizhou Medical University, Guiyang 561113, Guizhou, China Department of Traumatic Orthopedics, The Affiliated Hospital of Guizhou Medical University, Guiyang 550004, ...

Department of Pharmacy, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China Center of Clinical Pharmacology, the Third Xiangya Hospital, Central South University, ...

1Cellular Degradation Biology Center, College of Medicine, Seoul National University, Seoul, Republic of Korea. 2Department of Biomedical Sciences, College of Medicine, Seoul National University, ...

The following is a summary of “Expression and prognostic value of ferritinophagy-related NCOA4 gene in low-grade glioma: ...

kuleuven.be Intestinal resident macrophages are at the front line of host defence at the mucosal barrier within the gastrointestinal tract and have long been known to play a crucial role in the ...

Jan. 31, 2025 — In a new study, researchers have determined that a protein called NF-kB c-Rel can intensify the symptoms of psoriasis when activated by signals from the body's immune system ...