Daub's group also used stable-isotope labeling, phosphopeptide enrichment and LC-MS ... phosphorylation sites, demonstrating that in–depth coverage could be achieved without applying specific ...

BAD is a pro-apoptotic member of the Bcl-2 family that is tightly regulated by survival factors. Several major signalling pathways influence cell death through their direct effects on the ...

A thermal stability-based proteomic analysis identifies cytoplasmic PEBP1 as a mediator of mitochondrial dysfunction-induced stress response, highlighting its potential role in cellular adaptation ...

An emerging class of drugs, called Bruton's tyrosine kinase (BTK) inhibitors may alter this abnormal B cell respiration and stop the signaling that leads to MS flare-ups. The research, led by the ...