Tumor necrosis factor receptor 1 (TNFR1) is a single-spanning type I transmembrane protein with several cysteine-rich extracellular domains, and also known as one of the major receptors of TNFα. Due ...

Acute myeloid leukemia (AML) is an aggressive hematological malignancy ... This allows recognition by the autophagosomal sequestration machinery. Second, multiple mitophagic receptors (NIX/BNIPS, ...

Higher levels of soluble tumor necrosis factor (TNF) receptors were found in the stroma of control mice compared with the inflammasome-deficient mice. "It turned out that TNF receptors were being ...

Stromal-cell-derived factor 1 (SDF-1) plays a crucial role in hematopoiesis and has been implicated in acute myeloid leukemia (AML) pathogenesis. Understanding its relationship with chemotherapy ...

During the peer-review process the editor and reviewers write an eLife assessment that summarises the significance of the findings reported in the article (on a scale ranging from landmark to useful) ...