Explore the role of the extracellular matrix (ECM) in prostate cancer progression and discover natural therapies, including ...

School of Physics and Electronics, Key Laboratory of Low-dimensional Quantum Structures and Quantum Control of the Ministry of Education, Institute of Interdisciplinary Studies, Key Laboratory for ...

Integrins are very attractive therapeutic targets in oncology. The anti-tumor mechanisms of integrin-targeting drugs have been validated both in vitroand in vivo. Integrin-targeting drugs are ...

We discuss the challenges such as immunosuppressive microenvironment, tumor heterogeneity, and physical barriers that limit CAR-T efficacy. Emerging strategies, such as logic-gated and dual-targeting ...

Institute of Systems and Physical Biology, Shenzhen Bay Laboratory, Gaoke Innovation Center, Guangming District, Shenzhen, Guangdong 518132, P. R. China ...

The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in cancer cells. A tumor-suppressor gene, TP53 codes for a protein that inhibits the development and ...

PLN-101095 is under clinical development by Pliant Therapeutics and currently in Phase I for Solid Tumor. According to GlobalData, Phase I drugs for Solid Tumor have a 69% phase transition success ...

"Obesity is gradually eroding human health," and the global prevalence of obesity (BMI > 30) is predicted to reach 25 % by 2035, affecting nearly 1.9 billion people. The demand for medications to ...

16 in Nature Biotechnology, point to a potential new treatment that may benefit more patients than current therapeutic options. “Traditional therapies target one molecule in the tumor microenvironment ...

Here’s how it works. There's no doubt that cancer is deadly: In the United States, the disease is the second-most-common cause of death, after heart disease, according to the Centers for Disease ...

Many people have questions about how cancer can kill you. It is something that most people worry about at some point. We know that talking about this can be difficult. So, you can save to read this ...