This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

Atherosclerosis risk is elevated in diabetic patients, but the underlying mechanism such as the involvement of macrophages remains unclear. Here, we investigated the underlying mechanism related to ...

The BYD Sealion 6 medium SUV only arrived in Australia just over six months ago, but it’s already become the country’s best-selling plug-in hybrid vehicle. For 2024, the Sealion 6 beat out the ...

Department of Thoracic Surgery, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai 200433, China Institute of Functional Nano and Soft Materials, Jiangsu Key Laboratory for ...

M1 macrophages promote osteogenic transdifferentiation of vascular smooth muscle cells by secretion of IL-1β and TNF-α with concomitant increased mineralization ... activating transcription factor 6; ...

Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical studies have implicated macrophage-mediated immune tolerance. Hence, pathways ...

Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China ...

Current studies pictured the enteric nervous system and macrophages as modulators of neuroimmune processes in the inflamed gut. Expanding this view, we investigated the impact of enteric ...

Intraluminal vesicles from multivesicular bodies release exosomes into the extracellular space. Exosomes move to M0 macrophages and modulate the polarization into M1 and M2 under different stimulation ...