The discovery that RIPK1 deficiency sensitizes the liver to acute injury and hepatocyte apoptosis is based on convincing evidence, highlighting the importance of RIPK1 in maintaining liver homeostasis ...

He, H.J., Cen, X.H., Liang, Y.J., Zhong, J.M., Deng, J.H. and Jiang, Y.J. (2025) Progress in the Regulation of Lipid Metabolism by the Orphan Nuclear Receptor Nur77. Journal of Biosciences and ...

Department of Vascular Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, No. 1 Shuaifuyuan Hutong, Dongcheng District, Beijing 100730 ...

These compounds also exhibit superior pharmacokinetic properties, enhanced cancer cell inhibitory activity, and improved stability in human hepatocytes compared to existing reference compounds.

To investigate the potential contribution of hepatocyte cellular senescence to the metabolic derangements associated with non-alcoholic steatohepatitis (NASH), we treated human hepatocyte cell lines ...

In this millenium, we will be required to answer such questions as: Will it be possible to treat ischemic heart disease by stimulating myocardial angiogenesis, and will it be feasible to cure ...

Figure 2: Mechanisms and molecular mediators of adipose tissue angiogenesis. Combination therapies. It is likely that the combination of angiogenesis modulators with other targeted therapies for ...