The primary outcome of the study was the attainment of low disease activity at week 12, defined as a C-reactive protein (CRP) polymyalgia rheumatica activity score (PMR-AS) of 10 or less without oral ...

Induced pluripotent stem cells (iPSCs) are pluripotent stem cells generated from adult cells by reprogramming. iPSCs have the same properties as embryonic stem cells, and therefore self-renew and ...

Mitochondria are more than the powerhouses of the cell, they regulate a plethora of cellular processes such as apoptosis, metabolism and signaling. This exciting collection highlights the most recent ...

Alanyl-tRNA Synthetase 2 (AARS2) is a protein lysine lactyltransferase whose expression level is regulated by hypoxia-induced PHD2. Prior research has demonstrated that hypoxic conditions result in ...

uni-ulm.de Background Glucocorticoid (GC) therapy is frequently used to treat rheumatoid arthritis due to potent anti-inflammatory actions of GCs. Direct actions of GCs on immune cells were suggested ...

From the Department of Medicine, Medical College of Virginia, and the Medical Service, McGuire Veterans Administration Hospital. † Junior assistant resident in medicine, McGuire Veterans ...

In response to exercise, the heart rate speeds up, and blood vessels within tissues narrow (vasoconstriction). Exercise-induced vasoconstriction is triggered by the release of adrenaline, a hormone ...

Clinical Translational Research Center of Aggregation-Induced Emission, The Second Affiliated Hospital, School of Medicine, School of Science and Engineering, Shenzhen Institute of Aggregate Science ...

Clinical Translational Research Center of Aggregation-Induced Emission, School of Medicine, The Second Affiliated Hospital, School of Science and Engineering, The Chinese University of Hong Kong, ...

Glucocorticoid-induced myopathy is a characteristic symptom of endogenous Cushing's syndrome (CS). Its long-term outcome is largely unknown. OBJECTIVE: To evaluate long-term muscle function ...