The authors tried to elucidate the potential mechanism by which EUG inhibits the NRF2-mediated anti-oxidative stress pathway. Overall, this study is well executed with solid data, offering an ...

Want to apply for Canada PR? The country is set to introduce four new permanent residency (PR) pathways in 2025, even as the government plans to reduce its PR targets from 485,000 to 465,000, ...

Researchers have identified a key pathway that links how neurons send ... This research focuses on the cAMP-response element binding protein (CREB), a transcription factor known to regulate ...

We quantitatively compared seven OER pathways applicable to both the adsorbate evolution mechanism (AEM) and the lattice-oxygen-mediated mechanism (LOM) families, elucidating how iron significantly ...

Hope is not passive wishing but an active, dynamic process. According to Hope Theory, hope involves two components: agency and pathways. Agency is the belief in one’s capability to act ...

Introduction: Ulcerative colitis (UC), a form of inflammatory irritable bowel disease, is characterized by a recurrent and persistent nonspecific inflammatory response. Polydatin (PD), a natural ...

The results showed that CHIR99021 activated the GSK3β/β-catenin signaling pathway and reversed the PFOA-induced downregulation of ferroptosis markers GPX4 and SLC7A11 (Figure 6A-E&S4A-E). Previous ...

Conclusion: Taken together, our results indicated that DSI could protect against ferroptosis to attenuate renal fibrosis by activating the SIRT1/GPX4 pathway. It is expected to be a potential agent to ...

This discrepancy indicates that the etching procedure introduced extraneous conductive pathways unrelated to the VHE, thereby explaining why a reduced band gap had been observed in prior ...