来自MSN11 个月
Hooking an anchor on the DNA minor groove to facilitate gene expression during reprogramming
This revealed that the DNA-binding domain of Nr5a2 competes with a DNA minor groove anchor of the nucleosome and partially unwinds the DNA from the histones. "You can imagine it as if Nr5a2 were ...
Nature3 年
nucleosome / nucleosomes
A nucleosome is a section of DNA that is wrapped around a core of proteins. Inside the nucleus, DNA forms a complex with proteins called chromatin, which allows the DNA to be condensed into a ...