Results: The expression of the cell cycle regulators Bax/Bcl-2 ratio is not affected, along with no changes in p-38. On the other hand, an increase in oxidative stress markers, including those ...
This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...
Dose-dependent phosphoproteome profiling of four ATR inhibitors following DNA damage induction by GEM revealed a strong block of the DNA damage response pathway, including phosphorylated pS468 of ...
The researchers used preclinical models to explore the impact of stress on aging. They observed that social stress activates neurons in the hippocampus and cortex, showing signs of senescence and DNA ...
Since Los Angeles’ unprecedented January firestorms, the Eaton and Palisades fires have consumed nearly 40,000 acres of homes, businesses and landmarks in Altadena and Pacific Palisades and have ...
This is where DNA and RNA epigenetics come in: a series of mechanisms that act as "markers" on genes, to control their activity without modifying the DNA or RNA sequence itself. Until now ...