Results: The expression of the cell cycle regulators Bax/Bcl-2 ratio is not affected, along with no changes in p-38. On the other hand, an increase in oxidative stress markers, including those ...
Cellular senescence, where cells permanently stop dividing, plays a complex role in liver health. In a recent review article, researchers from China examined the mechanisms behind senescence, its ...
This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...
Dose-dependent phosphoproteome profiling of four ATR inhibitors following DNA damage induction by GEM revealed a strong block of the DNA damage response pathway, including phosphorylated pS468 of ...
How the TP53 Gene Works to Prevent Cancer TP53 is a protein whose main function is to repair DNA in order to prevent altered DNA from being passed on to daughter cells. When the damage in DNA is too ...
The researchers used preclinical models to explore the impact of stress on aging. They observed that social stress activates neurons in the hippocampus and cortex, showing signs of senescence and DNA ...
Since Los Angeles’ unprecedented January firestorms, the Eaton and Palisades fires have consumed nearly 40,000 acres of homes, businesses and landmarks in Altadena and Pacific Palisades and have ...