Expression levels of cholesterol 7α-hydroxylase, a key enzyme in bile acid synthesis, were similar in wild-type and ACAT2-deficient mice fed a chow diet and were suppressed in both groups of mice ...

While watching your diet, and avoiding a sedentary lifestyle are key factors to ensure that your cholesterol level does not shoot up, is there any way of finding out if these are working? The tricky ...

Free (unconjugated) bile acids were consistently demonstrated in ileal samples, and occasionally in lower jejunal samples, by thin-layer chromatography, supplemented in some cases by gas/liquid ...

Reduced receptor-mediated catabolism of LDL causes high plasma LDL cholesterol (LDL-C ... ezetimibe and bile acid sequestrants. In untreated HoFH, coronary heart disease usually develops in ...

Diacylglycerol acyltransferase (DGAT) is an enzyme that catalyzes the final step in TG synthesis ... Docosahexaenoic acid; EPA: Eicosapentaenoic acid; HDL-C: HDL cholesterol; LDL-C: LDL cholesterol.

Gallstones are broadly classified into 2 major types: cholesterol stones and pigment stones, with the former type being the most common. 5 They can develop either in the gallbladder or in the bile ...

Genomenon, Inc., a leading provider of genomic intelligence solutions, has announced a strategic partnership with Mirum Pharmaceuticals, Inc. to improve the awareness and diagnosis of Cerebrotendinous ...

INTERPRETATION/SUMMARY These results: (i) confirm that there are marked regional differences in bile acid metabolism between the right and left halves of the ... Twenty patients were studied (11 stone ...

ZJU-Hangzhou Global Scientific and Technological Innovation Centre, Hangzhou, Zhejiang 311200, China ...

Introduction High dietary saturated fat intake is associated with higher blood concentrations of low-density lipoprotein cholesterol (LDL-C), an established risk factor for coronary heart disease.

Neurons that secrete the neuropeptide orexin help mice decide between exercise and snacking.